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Cat. Number
733982440536459
Chemical Name
(R)-10-Monohydroxy-dihydro-carbamazepine
CAS Number
104746-03-4
Category
Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C15H14N2O2
Mol. Weight
254.28
Qty 1
5mg
Qty 2
50mg
Appearance
Off-White Solid
Application Notes
A metabolite of Eslicarbazepine acetate, (BIA 2-093) a novel central nervous system drug. ee=98% [α]d=-193 (C=1, pyridine)
Synonym
(10R)-10,11-Dihydro-10-hydroxy-5H-Dibenz[b,f]azepine-5-carboxamide; R-(-)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide; (R)-Licarbazepine; CGP 13698;
Melting Pt.
190-192°C
Solubility
Dichloromethane, DMSO, Methanol, Pyridine
Storage condition
-20?C Freezer
References
Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),
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