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Cat. Number
733982880237771
Chemical Name
Monastrol
CAS Number
254753-54-3
Category
Inhibitors,
Mol. Formula
C14H16N2O3S2
Mol. Weight
292.35
Qty 1
5mg
Qty 2
50mg
Appearance
Crystalline Solid
Application Notes
A cell-permeablesmall molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral spindles.
Synonym
6-Methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Melting Pt.
184-186°C
Solubility
DMSO, Ethanol, Ethyl Acetate
References
Mayer, T.U., et al.: Science, 286, 971 (1999), Kappe, C.O., et al.: Tetrahedron, 56, 1859 (2000)
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