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/ Products Classification 点击展开+| Cat. Number | 733982856451482 |
| Chemical Name | MK-886 |
| CAS Number | 118414-82-7 |
| Category | Inhibitors |
| Mol. Formula | C27H33ClNNaO2S |
| Mol. Weight | 494.0 |
| Qty 1 |
10mg |
| Qty 2 | 100mg |
| Appearance | White Solid |
| Application Notes | Binds to 5-lipoxygenase-activating protein with high affinity and prevents the activation of 5-lipoxygenase, thus inhibiting the biosynthesis of leukotrienes. |
| Synonym | 3-[tert-Butylthio-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropionic Acid, Sodium Salt |
| Melting Pt. | 295-297°C |
| Solubility | Dichloromethane, Ethanol, Methanol |
| Storage condition | Refrigerator |
| References | Dixon, R.A.F., et al.: Nature, 343, 282 (1990), Kargman, S., et al.: J. Biol. Chem., 266, 23745 (1991), Ford-Hutchinson, A.W.: Trends Pharmacol. Sci., 12, 63 (1991) |
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