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Cat. Number
733980277329027
Chemical Name
Mesna
CAS Number
19767-45-4
Category
Aliphatics, Sulfur & Selenium Compounds,
Mol. Formula
C2H5NaO3S2
Mol. Weight
164.18
Qty 1
1g
Qty 2
10g
Appearance
White to Off-White Solid
Application Notes
Mesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.
Synonym
2-Mercaptoethanesulfonic Acid Sodium Salt; 2-Mercapto-1-ethanesulfonic Acid Monosodium Salt; D 7093; Mesnex; Mistabron; Mistabronco; Mucofluid; Sodium 2-mercaptoethanesulfonate; UCB 3983; Uromitexan
Melting Pt.
>240°C dec.
Solubility
Water
Storage condition
-20˚C
References

Tekeres, M., et al.: Clin. Ther., 4, 56 (1981), Brock, N., et al.: Eur. J. Cancer Clin Oncol., 18, 1377 (1982), James, C.A., et al.: Br. J. Clin. Pharmacol., 23, 561 (1987), Schoenike, S.E., et al.: Clin. Pharm., 9, 179 (1990),

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