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Cat. Number
733980872307215
Chemical Name
Melphalan N-Oxide
CAS Number
685847-78-3
Category
Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C13H18Cl2N2O3
Mol. Weight
321.20
Qty 1
2.5mg
Qty 2
25mg
Application Notes
A derivative of Melphalan for treating diseased states associated with hypoxia-inducible factor; antitumor PX478 inhibitor hypoxia inducible factor.
Synonym
4-[Bis(2-chloroethyl)oxidoamino]-L-phenylalanine;
References
Isaacs, J., et al.: J. Biol. Chem., 277, 29936 (2002), Bachtiary, B., et al.: Clin. Cancer Res., 9, 2234 (2003), Koukourakis, M., et al.: J. Clin. Oncol., 24, 727 (2006),
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