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Cat. Number
733980873584936
Chemical Name
(+/-)-Lisofylline-d6
CAS Number
1185995-26-9
Category
Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C13H14D6N4O3
Mol. Weight
286.36
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Solid
Application Notes
A major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.
Synonym
3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-(dimethyl-d6)-1H-purine-2,6-dione; 1-(5-Hydroxyhexyl)theobromine�-d6; (+/-)-1-(5-Hydroxyhexyl)-3,7-(dimethyl-d6) xanthine; BL 194-d6; Pentoxifylline-d6 Alcohol;
Melting Pt.
126-128°C
Solubility
DMSO, Methanol
Storage condition
-20°C Freezer
References

 

Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996),
Itani, S., et al.: Metabolism, 50, 553 (2001),
Itani, S., et al.: Diabetes, 51, 2005 (2002),
Yu, C., et al.: J. Biol. Chem., 277, 50230(2002),

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