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Cat. Number
733980261544705
Chemical Name
LG 100268
CAS Number
153559-76-3
Category
Pharmaceuticals, Intermediates & Fine Chemicals, Retinoids,
Mol. Formula
C24H29NO2
Mol. Weight
363.49
Qty 1
5mg
Qty 2
50mg
Appearance
Off-White Solid
Application Notes
A potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).
Synonym
6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-Pyridinecarboxylic Acid; AGN 192620; ALRT 268; CD 3127; LG 268; LGD 100268; LGD 1268;
Melting Pt.
275-277?C
Solubility
Chloroform, Methanol
Storage condition
-20?C Freezer
References
Clyne, C., et al.: J. Biol. Chem., 277, 20591 (2002), Santen, R., et al.: J. Clin. Endocrinol. Metab., 87, 3007 (2002), Falender, A., et al.: Endocrinology, 144, 3598 (2003), Sablin, E., et al.: Mol. Cell., 11, 1575 (2003)
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