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Cat. Number
733980463606623
Chemical Name
(S)-Laudanosine
CAS Number
2688-77-9
Category
Aromatics, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C21H27NO4
Mol. Weight
357.44
Qty 1
10mg
Application Notes
Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
Synonym
(1S)-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline; Laudanosine; (+)-Laudanosine; (S)-(+)-Laudanosine; (S)-Laudanosine; L-(+)-Laudanosine; L-Laudanosine; (+)-Laudanosine, ; NSC 35045; O-Methylcodamine;
References
Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986), Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992), Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),
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