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Cat. Number
733980135831453
Chemical Name
Ko 143
CAS Number
461054-93-3
Category
Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C26H35N3O5
Mol. Weight
469.57
Qty 1
5mg
Qty 2
50mg
Application Notes
A potent BCRP (breast cancer resistance protein) inhibitor.
Synonym
(3S,6S,12aS)-,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic Acid 1,1-Dimethylethyl Ester;
References
Allen, J., et al.: Cancer Res., 59, 4237 (1999), van Loevezijn, A., et al.: Bioorg. Med. Chem. Lett., 11, 29 (2001), Raaijmakers, M., et al.: Clin. Cancer Res., 11, 2436 (2005),
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