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Cat. Number
733980511160413
Chemical Name
5-Keto Vioxx
CAS Number
179175-15-6
Category
Aromatics, Heterocycles, Impurities, Sulfur & Selenium Compounds
Mol. Formula
C17H12O5S
Mol. Weight
328.34
Qty 1
1mg
Qty 2
10mg
Application Notes
An impurity in Vioxx bulk drug, a possible contributor to chronic human toxicity.
Synonym
3-[4-(Methylsulfonyl)phenyl]-4-phenyl-2,5-furandione;
References
Sorbera, L., et al.: Drugs Future, 23, 1287 (1998), Halpin, R., et al.: Drug Metab. Dispos., 28, 1244 (2000), Nicoll-Griffith, D., et al.: Bioorg. Med. Chem. Lett., 10, 2683 (2000), Radhakrishna, T., et al.: J. Pharm. Boimed. Anal., 26, 617 (2001),
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