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Cat. Number
733979632514607
Chemical Name
Kenpaullone
CAS Number
142273-20-9
Category
Inhibitors
Mol. Formula
C16H11BrN2O
Mol. Weight
327.18
Qty 1
10mg
Qty 2
100mg
Appearance
Tan Solid
Application Notes
The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3? inhibitor (IC50=23nM).
Synonym
9-Bromo-7,12-dihydro-indolo[3,2-d][1]-benzazepin-6(5H)-one; 9-Bromopaullone
Solubility
DMSO
Storage condition
-20?C Freezer
References
Zaharevitz, D.W., et al.: Cancer Res., 59, 2566 (1999), Leclerc, S., et al.: J. Biol. Chem., 276, 251 (2001), Bain, J., et al.: Biochem. J., in press.
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