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Cat. Number
733979651374568
Chemical Name
Irinotecan Carboxylate Sodium Salt
Category
Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C33H39N4NaO7
Mol. Weight
626.68
Qty 1
5mg
Qty 2
50mg
Appearance
Pale Yellow Solid
Application Notes
Carboxylate form of Irinotecan, a DNA topoisomerase inhibitor.
Synonym
(αS)-2-[([1,4'-Bipiperidin]-1'-ylcarbonyl)oxy]-α,12-diethyl-9,11-dihydro-α-hydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid Sodium Salt; CPT 11 Carboxylic Acid Sodium Salt;
Melting Pt.
185-188°C
Solubility
DMSO
Storage condition
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
References
Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987), Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993), Chen, A., et al.: Annu. Rev. Pharmacol. Toxicol., 34, 191 (1994),
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