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Cat. Number
733979667083169
Chemical Name
Hydroxy Terbinafine β-D-Glucuronide
CAS Number
99473-12-8
Category
Glucuronides, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C27H33NO7
Mol. Weight
483.55
Qty 1
1mg
Qty 2
10mg
Appearance
Yellow Solid
Application Notes
A metabolite of Terbinafine, an orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis.
Synonym
(E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-ynyl β-D-Glucopyranosiduronic Acid;
Melting Pt.
105-107?C
Boiling Pt.
N/A
Solubility
Methanol
References

Gazinger, U., et al.: Proc. 13th Int. Congr. Chemother., 6, 116/52 (1983),
Shadomy, S., et al.: Sabouraudia, 23, 125 (1985),
Evans, E.G.V., et al.: Brit. Med. J., 318, 1031 (1999)

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