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/ Products Classification 点击展开+Cat. Number | 733978825432816 |
Chemical Name | 6-(2-Hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine |
CAS Number | 471270-60-7 |
Category | Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents |
Mol. Formula | C18H24N6O2 |
Mol. Weight | 356.43 |
Qty 1 |
5mg |
Qty 2 | 50mg |
Appearance | Off-White Solid |
Application Notes | An analogue of Olomoucine (Cat. # O567000) that acts as a potent inhibitor of Cdk 1 (IC50=100nm) and Cdk2 (IC50=80nm). Also displays antiproliferative and proapoptotic effects. |
Synonym | 2-[[[2-[(3-Hydroxypropyl)amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-phenol |
Solubility | Acetone, Dichloromethane, Methanol |
References | Wermeulen, K., et al.: Leukemia, 16, 299(2002) |