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Cat. Number
733978825432816
Chemical Name
6-(2-Hydroxybenzylamino)-2-(3-hydroxypropylamino)-9-isopropylpurine
CAS Number
471270-60-7
Category
Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents
Mol. Formula
C18H24N6O2
Mol. Weight
356.43
Qty 1
5mg
Qty 2
50mg
Appearance
Off-White Solid
Application Notes
An analogue of Olomoucine (Cat. # O567000) that acts as a potent inhibitor of Cdk 1 (IC50=100nm) and Cdk2 (IC50=80nm). Also displays antiproliferative and proapoptotic effects.
Synonym
2-[[[2-[(3-Hydroxypropyl)amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-phenol
Solubility
Acetone, Dichloromethane, Methanol
References

Wermeulen, K., et al.: Leukemia, 16, 299(2002)

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