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Cat. Number
733978816997353
Chemical Name
HC 030031
CAS Number
349085-38-7
Category
Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C18H21N5O3
Mol. Weight
355.39
Qty 1
50mg
Qty 2
500mg
Appearance
White Solid
Application Notes
A TRPA1 (transient receptor potential) selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.
Synonym
1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide;
Melting Pt.
221-223°C
Solubility
Chloroform, Methanol
Storage condition
Refrigerator, Under Inert Atmosphere
References

Jordt, S., et al.: Nature, 427, 260 (2004),
Macpherson, L., et al.: Curr. Biol., 15, 929 (2005),
Dai, Y., et al.: J. Clin. Invest., 117, 1979 (2007),
Doerner, J., et al.: J. Biol. Chem., 282, 13180 (2007),

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