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| Cat. Number | 733977669637893 |
| Chemical Name | Gleevec-d8 (Imatinib-d8) |
| Category | Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |
| Mol. Formula | C30H27D8N7O4S |
| Mol. Weight | 597.76 |
| Qty 1 |
0.5mg |
| Qty 2 | 5mg |
| Appearance | Yellow Solid |
| Application Notes | A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). |
| Synonym | 4-[(4-Methyl-1-piperazinyl-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide Methanesulfonate; CGP 57148B-d8; Gleevac-d8; Glivec-d8; Imatinib-d8 Mesilate; Imatinib-d8 Mesylate; STI 571-d8; |
| Melting Pt. | 119-124°C |
| Solubility | Chloroform, DMSO, Methanol |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| References |
Schindler, T., et al.: Science, 289, 1938 (2000), |
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