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Cat. Number
733977683472705
Chemical Name
4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
CAS Number
125971-96-2
Category
Aromatices, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C26H24FNO3
Mol. Weight
417.47
Qty 1
1g
Qty 2
10g
Appearance
White Solid
Application Notes
An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Synonym
2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic Acid Phenylamide;
Melting Pt.
196-1980C
Solubility
Chloroform
Storage condition
-20°C Freezer
References

Winters, R., et al.: J. Med. Chem., 36, 1735 (1993),
Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000),
Istvan, E., et al.: Science, 292, 1160 (2001)

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