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Cat. Number
733976407923986
Chemical Name
Estrone 3-O-Sulfamate
CAS Number
148672-09-7
Category
Steroids, Inhibitors,
Mol. Formula
C18H23NO4S
Mol. Weight
349.44
Qty 1
1mg
Qty 2
10mg
Appearance
White to Off-White Crystalline Solid
Application Notes
A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.
Synonym
Estrone 3-Sulfamate, Estrone O-Sulfamate, Estrone Sulfamate;
Melting Pt.
195-197°C
Solubility
DMSO, Methanol
Storage condition
-20°C Freezer
References

Woo, L.W., et al.: J. Med. Chem., 41, 1068 (1998)

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