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Cat. Number
733976874308117
Chemical Name
(+)-Emtricitabine
CAS Number
137530-41-7
Category
Carbohydrates & Derivatives, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C8H10FN3O3S
Mol. Weight
247.25
Qty 1
10mg
Application Notes
A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
Synonym
4-Amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (2S-cis)-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (+)-2’-Deoxy-3’-thia-5-fluorocytidine; (+)-FTC;
References

Mellors, J., et al.: Science, 72, 1167 (1996),
Reimann, K., et al.: J. Virol., 79, 8878 (2005),
Rose, J., et al.: J. Biol. Chem., 280, 7413 (2005),
Acierno, P., et al.: J. Immunol., 176, 5338 (2006),

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