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Cat. Number
733976894307858
Chemical Name
Eltrombopag
CAS Number
496775-61-2
Category
Agonist, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C25H22N4O4
Mol. Weight
442.47
Qty 1
5mg
Qty 2
50mg
Appearance
Orange to Red Solid
Application Notes
An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia
Synonym
3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB 497115
Melting Pt.
242-244°C
Solubility
DMSO
Storage condition
-20°C Freezer, Under Inert Atmosphere
References

Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007),
Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008),
Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),

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