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Cat. Number
733976639202945
Chemical Name
Efaproxiral
CAS Number
131179-95-8
Category
Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C20H23NO4
Mol. Weight
341.40
Qty 1
250mg
Qty 2
2.5g
Application Notes
Allosteric modifier of hemoglobin (HB). Binds in the central water cavity of the Hb molecule causing a conformational change such that bound oxygen is released more readily. Antineoplastic adjunct (radiosensitizer).
Synonym
2-[4-[2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoic Acid; RSR 13;
References

Abraham, D.J., et al.: Biochemistry, 31, 9141 (1992),
Pagel, P.S., et al.: J. Pharmacol. Exp. Ther., 285, 1 (1998),
Kleinberg, L., et al.: J. Clin. Oncol., 17, 2593 (1999),

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