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Cat. Number
733975492182026
Chemical Name
3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one
CAS Number
55314-16-4
Category
Amines, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C10H12N2O
Mol. Weight
176.22
Qty 1
1g
Qty 2
10g
Appearance
Off-White Solid
Application Notes
Imatinib intermediate.
Synonym
1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one; 3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one; 3-Dimethylamino-1-(pyridin-3-yl)propenone;
Melting Pt.
65-75°C
Solubility
Chloroform, Dichloromethane
References

Bennett, G., et al.: J. Med. Chem., 21, 623 (1978),
Buchdunger, E., et al.: J. Pharmacol. Exp. Ther., 295, 139 (2000),
Krystal, G., et al.: Clin. Cancer Res., 6, 3319 (2000),
van Oosterom, A., et al.: Lancet, 358, 1421 (2001),

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