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Cat. Number
733974844573503
Chemical Name
Desisobutyryl Ciclesonide-d11 (Mixture of Diastereomers)
Category
Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol. Formula
C28H27D11O6
Mol. Weight
481.67
Qty 1
1mg
Qty 2
10mg
Appearance
White Solid
Application Notes
Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma. This compound is a mixture of diastereomers at the cyclohexyl acetal.
Synonym
(11β,16α)-16,17-[[(R/S)-Cyclohexyl-d11-methylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione; CIC-AP-d11; Ciclesonide active principle-d11;
Melting Pt.
215-222°C
Solubility
Chloroform, Methanol
Storage condition
-20?C Freezer
References
Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).
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