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Cat. Number
733974497746607
Chemical Name
N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride
CAS Number
111974-74-4
Category
Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C17H19Cl2N3S
Mol. Weight
368.32
Qty 1
5mg
Qty 2
50mg
Appearance
Pale-Yellow Solid
Application Notes
A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
Synonym
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine, Dihydrochloride, DBTP,
Melting Pt.
180-184°C
Solubility
DMSO, Methanol
Storage condition
-20?C Freezer
References
DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),
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