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/ Products Classification 点击展开+| Cat. Number | 733973845639452 |
| Chemical Name | N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-β]pyridine |
| CAS Number | 303173-39-9 |
| Category | Isotope Labelled Compounds, Mutagenesis Research Chemicals, Nucleotides, Bases & Related Reagents |
| Mol. Formula | C23H20D3N9O4 |
| Mol. Weight | 492.51 |
| Qty 1 |
0.25mg |
| Qty 2 | 1mg |
| Appearance | Pale Yellow Solid |
| Application Notes | The deuterated DNA adduct formed from N-Hydroxy-PHIP. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). |
| Synonym | 2'-Deoxy-8-[[1-(methyl-d3)-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl]amino]guanosine; dG-C8-PhIP-d3; |
| Solubility | DMF, DMSO |
| Storage condition | Refrigerator |
| References | Frandsen, H., et al.: Carcinogenesis, 13, 4, 629 (1992), Lin, D., et al.: Chem. Res. Toxicol., 5, 691 (1993), Mizukami, S., et al.: Biochemistry, 45, 2772 (2006), |
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