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Cat. Number
733973760201719
Chemical Name
Dasatinib
CAS Number
302962-49-8
Category
Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Mol. Formula
C22H26ClN7O2S
Mol. Weight
488.01
Qty 1
10mg
Qty 2
100mg
Appearance
White to Off-White Solid
Application Notes
A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
Synonym
N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; BMS-354825;
Melting Pt.
275-286°C
Solubility
DMSO, Methanol
Storage condition
-20?C Freezer
References
Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004), Shah, N. P., et al.: Science, 305, 399 (2004), O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006),
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