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/ Products Classification 点击展开+Cat. Number | 733973534405395 |
Chemical Name | 8-Cyclopentyl-1,3-dipropylxanthine |
CAS Number | 102146-07-6 |
Category | Heterocycles, Inhibitors, Neurochemicals |
Mol. Formula | C16H24N4O2 |
Mol. Weight | 304.39 |
Qty 1 |
100mg |
Qty 2 | 1g |
Appearance | White Solid |
Application Notes | DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist. |
Synonym | 8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione; DPCPX, PD 116,948 |
Melting Pt. | 191-194°C |
Solubility | DMSO (3.6 mg/ml), Ethanol (4 mg/ml), 0.1N Sodium Hydroxide (2 mg/ml) |
Stability | Store tightly sealed at RT; Solutions at 4 deg C for several days |
References | Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008), |