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Cat. Number
733973710847537
Chemical Name
CP 141938
CAS Number
182822-62-4
Category
Aromatics, Chiral Reagents, Heterocycles, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C21H29N3O3S
Mol. Weight
403.54
Qty 1
10mg
Application Notes
CP-122721 and CP-141938 are potent and selective neurokinin-1 (NK1) receptor antagonists with very different brain disposition and potency in models of centrally mediated activity.
Synonym
rel-N-[4-Methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methyl-methanesulfonamide; cis-N-[4-Methoxy-3-[[(2-phenyl-3-piperidinyl)amino] methyl]phenyl]-N-methylmethanesulfonamide;
References
Barf, T., et al.: J. Med. Chem., 39, 4717 (1996), Chen, C., et al.: J. Pharmacol. Exp. Ther., 287, 545 (1998), Chen, C., et al.: Pharm. Res., 16, 296 (1999), Yamazaki, M., et al.: J. Pharmacol. Exp. Ther., 296, 723 (2001),
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