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Cat. Number
733972902743399
Chemical Name
Cilomilast
CAS Number
153259-65-5
Category
Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C20H25NO4
Mol. Weight
343.42
Qty 1
50mg
Appearance
White Solid
Application Notes
Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease.
Synonym
cis-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexanecarboxylic Acid; cis-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-4-cyanocyclohexane-1-carboxylic Acid; Ariflo; SB 207499;
Melting Pt.
157?C
References
Barnette, M.S., et al.: J. Pharmacol. Exp. Ther., 284, 420 (1998), Torphy, TJ., et al.: Pulm. Pharmacol. Ther., 12, 131 (1999), Zussman, B.D., et al.: Pharmacotherapy, 21, 653 (2001), Compton, C.H., et al.: Lancet, 358, 265 (2001),
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