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Cat. Number
733972920280091
Chemical Name
Cilastatin
CAS Number
82009-34-5
Category
Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C16H26N2O5S
Mol. Weight
358.45
Qty 1
10mg
Qty 2
100mg
Appearance
White to Light-Yellow Crystalline Powder
Application Notes
Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
Synonym
(2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid;MK-791;
Melting Pt.
156-158°C
Solubility
Methanol, Water
References
Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),
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