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Cat. Number
733972670082035
Chemical Name
(R)-Cetirizine Dihydrochloride
CAS Number
130018-77-8
Category
Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C21H27Cl3N2O3
Mol. Weight
461.81
Qty 1
10mg
Qty 2
100mg
Appearance
Off-White Solid
Application Notes
A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
Synonym
2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid Dihydrochloride; (-)-Cetirizine Dihydrochloride; Levocetirizine Dihydrochloride;
Melting Pt.
205-208°C (dec.)
Solubility
Water
Storage condition
-20?C Freezer
References
De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
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