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Cat. Number
733972547857588
Chemical Name
Casopitant Mesylate
CAS Number
414910-30-8
Category
Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C31H39F7N4O5S
Mol. Weight
712.72
Qty 1
10mg
Application Notes
It is a novel, orally active tachykinin NK1 receptor antagonist; efficacy of Casopitant mesilate in patients receiving emetogenic chemotherapy.
Synonym
(2R,4S)-4-(4-Acetyl-1-piperazinyl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-1-piperidinecarboxamide Methanesulfonate; GW 679769B;
References
Hesketh, P., et al.: Eur. J. Cancer., 39, 1074 (2003), Kris, M., et al.: J. Clin. Oncol., 24, 2932 (2006), Minthorn, E., et al.: Drug Metab. Dispos., 36, 1846 (2008),
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