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Cat. Number
733970322063322
Chemical Name
Brefeldin A
CAS Number
20350-15-6
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C16H24O4
Mol. Weight
280.36
Qty 1
5mg
Qty 2
50mg
Appearance
White Powder
Application Notes
A macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.
Synonym
γ-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ?-Lactone, BFA, Cyanein, Ascotoxin, Decumbin; NSC 244390; NSC 56310; NSC 89671; Nectrolide; Synergisidin;
Melting Pt.
206-208?C
Solubility
Methanol
Storage condition
-20?C Freezer
References
Misumi, Y., et al.: J. Biol. Chem., 261 (1986), Mordente, J.A., et al.: J. Urol., 159, 275 (1998), Erokhina, M.V., et al.: Membr. Cell Biol., 12, 871 (1999), Nojiri, H., et al.: FEBS Letters, 453, 140 (1999),
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