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/ Products Classification 点击展开+| Cat. Number | 733970271608964 |
| Chemical Name | Bisindolylmaleimide VIII |
| CAS Number | 125313-65-7 |
| Category | Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol. Formula | C24H22N4O2 |
| Mol. Weight | 398.46 |
| Qty 1 |
10mg |
| Qty 2 | 100mg |
| Application Notes | It is a potent inhibitor of protein kinase C (PKC) activity. Bisindolylmaleimide VIII (Bis VIII) has been previously shown to enhance Fas-mediated apoptosis through a protein kinase C-independent mechanism. |
| Synonym | 3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)- 1H-pyrrole-2,5-dione;
Ro 31-7549; Ro 31-7549/001;
|
| References | Emery, J., et al.: J. Biol. Chem., 273, 14363 (1998), Wiley, S., et al.: Immunity, 3, 673 (1995), MacFarlane, M., et al.: Biochem. J., 348, 93 (2000), |
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