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Cat. Number
733970184688158
Chemical Name
(R)-Bicalutamide
CAS Number
113299-40-4
Category
Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol. Formula
C18H14F4N2O4S
Mol. Weight
430.37
Qty 1
5mg
Qty 2
50mg
Appearance
Off-White Crystalline Solid
Application Notes
(R)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).
Synonym
(2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex;
Melting Pt.
178-181°C
Solubility
Ethyl Acetate
References
Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),
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