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Cat. Number
733969104475932
Chemical Name
O6-Benzylguanine
CAS Number
19916-73-5
Category
Nucleotides, Bases & Related Reagents
Mol. Formula
C12H11N5O
Mol. Weight
241.25
Qty 1
50mg
Qty 2
500mg
Appearance
Light Yellow Solid
Application Notes
An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.
Synonym
6-(Phenylmethoxy)-9H-purin-2-amine; 2-Amino-6-(benzyloxy)purine; NSC 637037;
Melting Pt.
193°C dec.
Solubility
Aqueous Alkali
Storage condition
-20?C Freezer
References
Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)
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