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Cat. Number
733969919127743
Chemical Name
Balanol
CAS Number
63590-19-2
Category
Aromatics, Chiral Reagents, Heterocycles, Inhibitor, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C28H26N2O10
Mol. Weight
550.51
Qty 1
10mg
Application Notes
Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncology.
Synonym
4-(2-Carboxy-6-hydroxybenzoyl)-3,5-dihydroxybenzoic Acid (3R,4R)-Hexahydro-3-[(4-hydroxybenzoyl)amino]-1H-azepin-4-yl Ester; (3R-trans)-Balanol; (-)-Balanol; Azepinostatin; Ophiocordin;
References
Crane, H., et al.: Bioorg. Med. Chem. Lett., 5, 2133 (1995), Lai, Y., et al.: J. Med. Chem., 40, 226 (1997), Narayana, N., et al.: Biochemistry, 38, 2367 (1999),
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