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Cat. Number
733969931590395
Chemical Name
Bafetinib
CAS Number
859212-16-1
Category
Aromatics, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C30H31F3N8O
Mol. Weight
576.62
Qty 1
5mg
Qty 2
10mg
Application Notes
A substituted benzamide derivative structurally related to STI-571 (Imatinib Mesylate). It was identified as highly potent Bcr-Abl kinase inhibitor.
Synonym
N-[3-([4,5'-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide; INNO 406; NS 187;
References
Li, Q., et al.: J. Med. Chem., 39, 3070 (1996), Ptasznik, A., et al.: Nat. Med., 10, 1187 (2004), Tetsuo, A., et al.: Bioorg. Med. Chem. Lett., 16, 1421 (2006),
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