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Cat. Number
733968615118760
Chemical Name
Atorvastatin Lactone
CAS Number
125995-03-1
Category
Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C33H33FN2O4
Mol. Weight
540.62
Qty 1
25mg
Qty 2
250mg
Appearance
Slightly Yellow Solid
Application Notes
Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.
Synonym
5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin δ-Lactone;
Melting Pt.
103-106°C
Solubility
DMF, DMSO, Ethyl Acetate, Methanol
Storage condition
-20?C Freezer, Under Inert Atmosphere
References
Boyd, R., et al.: J. Clin. Pharmacol., 40, 91, (2000), Bogman, K., et al.: Br. J. Pharmacol., 132, 1183 (2001), Backman, J., et al.: Clin. Pharmacol. Ther., 72, 685 (2002), Kalvass, J., et al.: Drug Metab. Dispos., 35, 455(2007),
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