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/ Products Classification 点击展开+Cat. Number | 733968615118760 |
Chemical Name | Atorvastatin Lactone |
CAS Number | 125995-03-1 |
Category | Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, |
Mol. Formula | C33H33FN2O4 |
Mol. Weight | 540.62 |
Qty 1 |
25mg |
Qty 2 | 250mg |
Appearance | Slightly Yellow Solid |
Application Notes | Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation. |
Synonym | 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin δ-Lactone; |
Melting Pt. | 103-106°C |
Solubility | DMF, DMSO, Ethyl Acetate, Methanol |
Storage condition | -20?C Freezer, Under Inert Atmosphere |
References | Boyd, R., et al.: J. Clin. Pharmacol., 40, 91, (2000), Bogman, K., et al.: Br. J. Pharmacol., 132, 1183 (2001), Backman, J., et al.: Clin. Pharmacol. Ther., 72, 685 (2002), Kalvass, J., et al.: Drug Metab. Dispos., 35, 455(2007), |