服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | 733968135419747 |
Chemical Name | Amonafide |
CAS Number | 69408-81-7 |
Category | Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
Mol. Formula | C16H17N3O2 |
Mol. Weight | 283.33 |
Qty 1 |
10mg |
Qty 2 | 100mg |
Application Notes | Amonafide is a DNA intercalator and topoisomerase II inhibitor in clinical development for the treatment of neoplastic diseases. Antitumor agent. |
Synonym | 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione; FA 142; M-FA 142; MADE-FA 142; NCI 308847; NSC 308847; Nafidimide; |
References | Hsiang, Y., et al.: Mol. Pharmacol., 36, 371 (1989), Costanza, M., et al.: Clin. Cancer Res., 1, 699 (1995), Innocenti, F., et al.: Drug Metab. Dispos., 29, 596 (2001), Brana, M., et al.: J. Med. Chem., 47, 1391 (2004), |