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Cat. Number
733968382132695
Chemical Name
(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
CAS Number
74341-63-2
Category
Heterocycles, Neurochemicals
Mol. Formula
C7H10N2O4
Mol. Weight
186.17
Qty 1
10mg
Qty 2
100mg
Appearance
White-to-Off White Powder
Application Notes
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
Synonym
D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid; AMPA; D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid; γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid;
Melting Pt.
240-250°C dec.
Stability
Store in freezer at -20°C
References
Krogsgaard-Larsen, et al.: Nature, 284, 64 (1980), Honore, T., et al.: J. Neurochem., 38, 173 (1982), MacDonald, J.F., et al.: Science, 253, 1132 (1991)
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