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Cat. Number
733968571786838
Chemical Name
N-(2-Aminoethyl) Cyclopamine
CAS Number
334616-31-8
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol. Formula
C29H46N2O2
Mol. Weight
454.69
Qty 1
0.25mg
Qty 2
2.5mg
Appearance
Off-White Solid
Application Notes
A deriviative of Cyclopamine, which demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1
Synonym
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-4'-(2-aminoethyl)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Melting Pt.
188-200°C
Solubility
Chloroform, Methanol
Storage condition
-20?C Freezer
References
Taipale, J., et al.: Nature, 406, 1005 (2000), Perron, M., et al.: Development, 130, 1565 (2003)
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