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/ Products Classification 点击展开+| Cat. Number | 733967202498948 |
| Chemical Name | Aloisine RP106 |
| CAS Number | 496864-15-4 |
| Category | Aromatics, Heterocycles, Inhibitors, Protein Kinase Inhibitors and Activators |
| Mol. Formula | C17H19N3O |
| Mol. Weight | 281.35 |
| Qty 1 |
10mg |
| Qty 2 | 100mg |
| Appearance | Off-white Solid |
| Application Notes | A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk1/cyclin B, Cdk5/p35, and GSK-3 ( IC50 =700nM 1.5 uM, and 920 nM, respectively).
|
| Synonym | RP106, 7-n-Butyl-6-(4-methoxyphenyl)-[5H]pyrrolo[2,3-b]pyrazine; |
| Melting Pt. | 182-184°C |
| Solubility | DMSO |
| Storage condition | -20?C Freezer |
| References | Mattey, Y., et al.: J. Med. Chem., 46, 222 (2003) |
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