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Cat. Number
733967151378557
Chemical Name
N-[4-(1-Allyl-3-butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl)phenyl]acetamide
CAS Number
628279-02-7
Category
Aromatics, Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C21H25N5O3
Mol. Weight
395.45
Qty 1
10mg
Qty 2
100mg
Application Notes
It is used for the preparation of amide-substituted xanthine derivatives as phosphoenolpyruvate carboxykinase inhibitors with gluconeogenesis modulating activity for treating type 2 diabetes.
Synonym
N-[4-[[3-Butyl-2,3,6,9-tetrahydro-2,6-dioxo-1-(2-propen-1-yl)-1H-purin-8-yl]methyl]phenyl]acetamide;
References
Kawashima, Y., et al.: Chem. Pharm. Bull., 43, 1132 (1995), Sun, Y., et al.: J. Biol. Chem., 277, 23301 (2002), Foley, L., et al.: Bioorg. Med. Chem. Lett., 13, 3871 (2003),
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