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/ Products Classification 点击展开+| Cat. Number | 733967429429720 |
| Chemical Name | AEE 788 |
| CAS Number | 497839-62-0 |
| Category | Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |
| Mol. Formula | C27H32N6 |
| Mol. Weight | 440.58 |
| Qty 1 |
10mg |
| Application Notes | A novel dual receptor tyrosine kinase inhibitor of the EGF and the VEGF receptor, for treatment of human HCC cell lines and in a s.c. xenograft model. |
| Synonym | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine; [6-[4-[(4-Ethylpiperazin-1-yl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin
-4-yl]-((R)-1-phenylethyl)amine ; NVP-AEE 788; |
| References | Ito, Y., et al.: Br. J. Cancer., 84, 1377 (2001), Huether, A., et al.: Biochem. Pharmacol., 70, 1568 (2005), Zhu, A., et al.: J. Clin. Oncol. 24, 1898 (2006), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007), |
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