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Cat. Number
733967985901985
Chemical Name
3-O-Acetyl Ezetimibe-d4 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester
Category
Aromatics, Glucuronides, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C39H35D4F2NO13
Mol. Weight
771.75
Qty 1
1mg
Qty 2
10mg
Appearance
White Solid
Application Notes
Labelled intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor.
Synonym
4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl-d4)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate
Solubility
Dichloromethane
References
Mutlib, A., et al.: Drug Metab. Dispos., 20, 451 (1992), Clader, J., et al.: J. Med. Chem., 39, 3684 (1996), van Heek, M., et al.: J. Pharmacol. Exp. Ther., 283, 157 (1997),
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