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Cat. Number
733967627033585
Chemical Name
N-(4-Acetamidophenyl)indomethacin Amide
CAS Number
261766-23-8
Category
Aromatics, Heterocycles, Inhibitors,
Mol. Formula
C27H24ClN3O4
Mol. Weight
489.95
Qty 1
50mg
Qty 2
500mg
Appearance
Pale Yellow Solid
Application Notes
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.1 uM and 0.625 uM, respectively.
Synonym
N-(4-Acetamidophenyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide
Melting Pt.
256-257°C
Storage condition
-20?C Freezer
References
Kalgutkar, A.S., et al.: J. Med. Chem., 43, 2860 (2000), Holt, S., et al.: Eur. J. Pharmacol., 565, 26 (2007),
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