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/ Products Classification 点击展开+| Cat. Number | 733966494209147 |
| Chemical Name | ABT 263 |
| CAS Number | 923564-51-6 |
| Category | Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
| Mol. Formula | C47H55ClF3N5O6S3 |
| Mol. Weight | 974.61 |
| Qty 1 |
5mg |
| Qty 2 | 50mg |
| Appearance | Pale Yellow Solid |
| Application Notes | A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate. |
| Synonym | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide; |
| Melting Pt. | 114-116°C |
| Solubility | Chloroform, DMSO, Methanol |
| Storage condition | -20?C Freezer, Under Inert Atmosphere |
| References | Adams, J., et al.: Science, 281, 1322 (1998), Degterev, A., et al.: Nat. Cell. Biol., 3, 173 (2001), Kitada, S., et al.: J. Med. Chem., 46, 4259 (2003), Danial, N., et al.: Clin. Cancer Res., 13, 7254 (2007), |
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